diff --git a/pyproject.toml b/pyproject.toml
index 6ffe5b5..6823105 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -47,7 +47,7 @@ dependencies = [
     "networkx>=2.8,<4.0",
     "waterEntropy>=2,<3.0",
     "requests>=2.32.2,<3.0",
-    "rdkit>=2025.3.4,<2026",
+    "rdkit>=2026.3.6,<2027",
     "numba>=0.63.0,<0.70",
     "dask>=2025.4.0,<2027.1.0",
     "dask-jobqueue>=0.9.0,<1.0",