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  • Pontificial University Catholic of Chile
  • Santiago, Chile

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PALP31/README.md
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πŸ”¬ Multi-Omics & Plant Physiology Research Framework

Multi-Omics Research Framework

  • πŸŽ“ University Teaching (PUC): Lecturer of the undergraduate course Statistical Applications (Aplicaciones EstadΓ­sticas) at the Pontificia Universidad CatΓ³lica de Chile, training students in statistical inference, experimental design, linear models, and applied data analysis in R.
  • 🌾 PhD Research & Multi-Omics: PhD Candidate in Plant Biotechnology (PUC), focused on abiotic stress tolerance (heat and drought) in crops through the integration of Ionomics ($K^+/Na^+$, micronutrients), Transcriptomics (RNA-seq / DESeq2 / WGCNA), and Metabolomics (antioxidant profiling, compatible solutes, proline, MDA).
  • 🦠 Agricultural Microbiology & Biocontrol: Quantitative modeling of plant-beneficial microbe interactions: antagonistic dynamics of Trichoderma spp. (mycoparasitism, volatile organic compounds VOCs, dual-culture inhibition), Plant Growth-Promoting Rhizobacteria (PGPR: Bacillus, Pseudomonas), dual inoculation/consortia, biomineral solubilization ($P$, $K$, siderophores), and microbe-mediated abiotic stress mitigation.
  • 🎲 Bayesian Statistics & MCMC Inference: Advanced Bayesian hierarchical modeling with brms and Stan, calibration of informative and regularizing priors, MCMC convergence diagnostics ($\hat{R}$, ESS, trace plots), leave-one-out cross-validation (LOO-CV / WAIC), and Posterior Predictive Checks.
  • πŸ•ΈοΈ Structural Equation Modeling (Piecewise SEM): Disentangling direct and indirect effects in multilayer physiological networks, integrating hierarchical mixed submodels and directional separation (d-sep) tests.
  • πŸ’» Scientific Software Development: Creator and author of the R packages agriDesignR (v0.2.1, assisted experimental design engine, 2D micro-layouts, and hierarchical mixed models) and easyModels (v0.4.2, automated and reproducible biostatistics), designed to translate cutting-edge methodological workflows to the university classroom and high-impact scientific research.

πŸ› οΈ Tech Stack & Computational Tools

Domain Technologies & Libraries
Languages R Python Bash SQL
Bayesian Statistics & Modeling Stan easyModels piecewiseSEM lme4 glmmTMB mgcv (GAMs) brms bayesplot tidybayes drc emmeans DHARMa
Experimental Design agriDesignR agricolae emmeans desplot Alpha-Lattice Split-Plot RCBD Power Analysis
Multi-Omics & Bioinformatics DESeq2 mixOmics (sPLS-DA) WGCNA Bioconductor tidyverse ggplot2 pheatmap ComplexHeatmap
Microbiome & Biocontrol Dose-Response (drc) Dual-Culture Kinetics PhytoMicrobiome Stats Bioassays Phenotyping
Publishing & Reproducibility Quarto RMarkdown LaTeX Obsidian
Environments, IDEs & AI Agents RStudio VSCode PyCharm Antigravity Codex Claude Code
DevOps & Systems Git GitHub Actions uv macOS Linux

πŸš€ Featured R Packages & Ecosystems

agriDesignR hex logo

🌱 agriDesignR (v0.2.1) β€” Assisted Experimental Design Engine & Mixed Models

R Package CRAN Ready CI Shiny GUI Engines License

Intelligent decision engine for agricultural and biological sciences. Connects the complete workflow: Pre-Trial Planning (greenhouse/field gradient diagnostics, replication calculator, 2D bench layouts, and sowing CSV templates), Multi-Engine Mixed Modeling (Kenward-Roger LMM, GLMM, non-parametric tests), Automated Diagnostic Remediation (Box-Cox, varIdent, Gamma/NB GLMM), Relative Blocking Efficiency (Cochran & Cox), Simple Effects in 2- & 3-Way Factorials, Publication-Ready Figures (Nature style), and an Interactive Web App (launch_app()).

remotes::install_github("PALP31/agriDesignR@v0.2.1")

easyModels hex logo

πŸ“¦ easyModels (v0.4.2)

R Package Status

R package for applied and reproducible biostatistics. Features a unified S3 architecture (easy_model), automated fitting for LM, GLM, LMM, and GLMM, standard experimental designs (RCBD, Split-Plot, Latin Square, Repeated Measures), automated assumption diagnostics (verificar_supuestos), model selection via AIC/BIC, and publication-ready plots with Tukey grouping letters.

🦠 Plant-Microbiome-Biocontrol

Microbiome Biocontrol

Platform for quantitative modeling and experimental analysis of plant-microbe interactions: Trichoderma antagonistic kinetics, plant growth-promoting rhizobacteria (PGPR: Bacillus, Pseudomonas), dual consortia, mineral solubilization ($P, K$), and mitigation mechanisms under salinity, drought, and heat stress.

πŸ“Š BioAgro-Stats

BioAgro-Stats Bayesian

Structured 8-module repository for advanced biostatistics: from assumption auditing, experimental designs, and non-linear dose-response curves (log-logistic DRC) to Bayesian modeling with brms, Machine Learning (Random Forest, XGBoost), and physiological PCA biplots.

🌾 Triticum Tale Web

Quarto Data Art

Scientific web portal and interactive Data Storytelling platform built with Quarto/Plotly to visually communicate multi-omics and physiological stress responses in Triticum durum under heat and drought stress.


πŸ“‹ Specialized Repositories & Research Ecosystems

Repository Specialty & Focus Direct Link
🌱 agriDesignR Assisted Experimental Design Engine, Mixed Models & Shiny GUI View Repository β†—
πŸ“¦ easyModels R package for automated biostatistics and mixed models View Repository β†—
🦠 Plant-Microbiome-Biocontrol Trichoderma, PGPR, endophytes, biocontrol & abiotic stress mitigation View Repository β†—
πŸ“Š BioAgro-Stats Statistical modules for agronomy, DRC, GAMs & Machine Learning View Repository β†—
🌾 Triticum-tale-web Interactive Quarto/Plotly platform for crop stress responses View Repository β†—
πŸ“ Experimental-Design-Lab RCBD, Split-Plot, Latin Squares, Alpha-Lattice & Power Analysis View Repository β†—
πŸ“ˆ Statistical-Modeling-Mastery Progressive modeling roadmap: from LM/GLM to DRC, GAMs & Bayesian View Repository β†—
🌾 Plant-MultiOmics-Framework Ionomics, RNA-seq Transcriptomics, Metabolomics & sPLS-DA View Repository β†—
🎲 Bayesian-Biostats Bayesian Modeling with brms/Stan, MCMC & Piecewise SEM View Repository β†—

πŸ“Š Scientific Software Ecosystem & Development Metrics

Scientific Software and Computational Research Ecosystem


Footer Wave Pontificia Universidad CatΓ³lica de Chile β€’ University Teaching & Plant Biotechnology Research

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