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@biocypher @REPO4EU @omiydev

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fmdelgado/README.md

Fernando M. Delgado-Chaves

I build and evaluate LLM and agent systems for biomedical research. PhD from Pablo de Olavide University, Seville; working in computational biology since 2017. Based in Hamburg.

Selected work

  • LLM_SR_medicine — the screening pipeline behind my first-author PNAS 2025 paper measuring LLM literature screening against human ground truth. doi:10.1073/pnas.2411962122
  • academatepy — AcadeMate, a systematic-review agent built around PRISMA methodology. Developed at CoSy.Bio, University of Hamburg.
  • DRACOONpy — a differential co-expression algorithm; pip install dracoonpy. First author, BMC Bioinformatics 26:137 (2025). doi:10.1186/s12859-025-06162-9
  • drugrepochatter — ChatDRex, an agentic drug-repurposing system built for the EU REPO4EU consortium.

Contributions to other people's code

A logged-out GitHub profile does not render pull requests merged into other organisations, so this work is invisible here by default.

Why this account looks quiet

Roughly 94% of the ~2,200 commits I have authored are in private repositories: a company codebase, and clinical-data projects covered by data-use agreements. What is public here is the academic tooling I am free to publish.

Galagos

I co-founded Galagos GmbH, a University of Hamburg spin-out building an agentic AI system for bioinformatics, and led it as CTO. The company is being wound down — runway and market timing did not line up. I would rather go deep as a builder than run a company.

Elsewhere

Pinned Loading

  1. LLM_SR_medicine LLM_SR_medicine Public

    Code behind Delgado-Chaves et al., PNAS 122(2):e2411962122 (2025): benchmarking how well LLMs screen titles and abstracts for systematic reviews in medicine against human reviewer decisions. LangCh…

    HTML 4 1

  2. DRACOONpy DRACOONpy Public

    DRaCOoN: data-driven differential co-expression and differential regulatory network inference from transcriptomics data across two conditions (BMC Bioinformatics 2025)

    Jupyter Notebook 3 1

  3. drugrepochatter drugrepochatter Public

    LLM-based drug repurposing assistant (DrugRepoChatter/ChatDRex): a retrieval-augmented chatbot over a REPO4EU-curated corpus of drug repurposing literature

    Python 1 2

  4. academatepy academatepy Public

    AcadeMate: an AI-powered framework that automates PRISMA-compliant systematic literature reviews end-to-end using LLMs, embeddings and RAG, with the researcher kept in the loop.

    Jupyter Notebook

  5. fernandodelgado.me fernandodelgado.me Public

    Personal CV site — AI engineer for the life sciences

    HTML