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sashachernenkoff/README.md

Hi, I'm Sasha 👋

I'm a machine learning engineer specializing in PyTorch, building and training deep learning architectures for genomic applications. My work centers on representation learning, using techniques like custom loss functions, distributed training (DDP), and parameter-efficient fine-tuning (LoRA). Domain background in genomics and clinical diagnostics informs the problems I build for.

🌱 Currently learning: cloud infrastructure for ML training and deployment (AWS)

📫 sjchernenkoff@gmail.com · sashachernenkoff.com

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  1. pastl pastl Public

    Foundation model empowered transfer learning (PyTorch, custom biologically-gated attention head) to predict cis-regulated protein abundance. Analysis suite for interpretability and validation inclu…

    Python

  2. herl herl Public

    Deep generative modelling (PyTorch, categorical VAE) and representation learning of high-dimensional genotype data for heritability estimation.

    Python

  3. nf-germline-variant-calling nf-germline-variant-calling Public

    GATK best-practices germline variant-calling pipeline built in Nextflow. Originally validated on CPTAC LUAD (~230 samples); public version runs on GIAB reference data. Containerized, resumable, por…

    HTML 1

  4. variant-prior-pwas variant-prior-pwas Public

    A generalized pipeline for evaluating variant effect predictors by using their scores as biological priors in TWAS/PWAS

    Python 1

  5. davidenoma/DL_cancer_drug_response davidenoma/DL_cancer_drug_response Public

    Predicting patient drug responses using gene expresions, drugs SMILES and advanced deep learning techniques

    Jupyter Notebook 5 1

  6. MDGE612project MDGE612project Public

    Predicting phenotype from genotype: a comparison of Lasso and Ridge regression

    Python 1