Reusable, unit-tested R methods for isoform-level single-cell RNA-seq: fractional isoform-to-gene collapse, isoform switching and deltaPI, effect sizes.
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Updated
Sep 23, 2026 - R
Reusable, unit-tested R methods for isoform-level single-cell RNA-seq: fractional isoform-to-gene collapse, isoform switching and deltaPI, effect sizes.
A Python tool that detects driver isoforms by measuring topological perturbations in isoform-resolved protein interaction networks. Combines domain-gated PPI inference with augmented Forman-Ricci curvature and a compact classifier on per-sample geometric features.
Is this functional isoform-class comparison measurable by short reads? Group-level identifiability, quantification and testing from bulk RNA-seq
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