transposase

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ahmedanees-m / mech-class

Two-tier classifier for the catalytic mechanism of programmable genome-writing enzymes, with a biochemical gate that correctly labels IS110-family composite recombinases.

machine-learning bioinformatics computational-biology lightgbm crispr crispr-cas9 genetic-engineering gene-editing esm-2 recombinases transposase bridgerna genome-atlas mechanism-classifier

Updated Jul 15, 2026
Python

ahmedanees-m / genome-atlas

Star

Knowledge graph and GNN benchmark for programmable genome-writing enzymes, with ESM-2 embeddings, GraphSAGE/GAT link prediction, and an editor-selection API.

machine-learning bioinformatics computational-biology pytorch knowledge-graph crispr crispr-target crispr-cas9 artifical-intelligence gnn graphneuralnetworks crispr-design torchgeometric esm-2 recombinases transposase bridgerna genetic-en genome-en

Updated Jul 16, 2026
Python

ahmedanees-m / pen-score

Star

Multi-axis scoring framework that ranks programmable genome editors across eight orthogonal axes into a single PenScore to guide experimental design and benchmarking.

machine-learning bioinformatics computational-biology crispr crispr-cas9 genome-editing genetic-engineering gene-therapy base-editors recombinases scoring-framework transposase genome-atlas mech-class prime-editors therapeutic-genome-editing pen-assemble

Updated Jul 16, 2026
Python

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